Heat a small frying pan on med-low. Add blueberries, vinegar and water. Lightly cook down to a sauce. Season with salt and pepper. Set aside.
Heat a large frying pan on medium. Butter 1 side of 2 of the slices of bread. Place brie on non-buttered side. Fry the bead until cheese is melted and bread is golden. Remove from heat.
Place 1 brie slice on a plate and top with 2 bacon strips. Top with a bread slice. Spoon blueberry sauce evenly. Top with a bread slice and top with 2 bacon strips. Finally top with 2nd brie slice. Cut in half.